TRee-based Exploration of Neighborhoods and Domains

Maintenance works will be carried out May-26-2020 at 11:00 (EDT). We ask you to finish your jobs prior to this date. The server will be stopped and the running jobs will be lost. The server will start working May-26-2020 at 14:00 (EDT).

Set options

Redundancy (CD-HIT):

Alignment (Mafft):

Alignment Algorithm:

Tree Building:

A.A. Substitution Model:
Phylogeny Test:
Number of replicates:
Tree Building Method:
A.A. Substitution Model:
A.A. Substitution Model:
A.A. Substitution Rate:
Initial tree for ML:
Gaps and Missing Data:
Site Coverage Cutoff:
Phylogeny Test:
Phylogeny Test:
Number of replicates:

Gene neighbors:

Number of neighboring genes on one side (max 15):
Operon tolerance:
Not shared domains tolerance:


Wrong format. Expected sequences in fasta format or tree in newick format. To start the analysis you need to choose a file or paste its content in the area above. There should be at least 3 protein sequences to start the analysis. Malformed newick tree. Please correct the tree. You can't both provide sequences and check 'Retrieve sequences'